Read our work
2024
Insights into phosphate homeostasis regulation by XPR1
Daniel P Bondeson
2022
Systematic profiling of conditional degron tag technologies for target validation studies
Daniel P. Bondeson, Zachary Mullin-Bernstein, Sydney Oliver, Thomas A. Skipper, Thomas C. Atack, Nolan Bick, Meilani Ching, Andrew A. Guirguis, Jason Kwon, Carly Langan, Dylan Millson, Brenton R. Paolella, Kevin Tran, Sarah J. Wie, Francisca Vazquez, Zuzana Tothova, Todd R. Golub, William R. Sellers, Alessandra Ianari
Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer
Daniel P. Bondeson, Brenton R. Paolella, Adhana Asfaw, Michael V. Rothberg, Thomas A. Skipper, Carly Langan, Gabriel Mesa, Alfredo Gonzalez, Lauren E. Surface, Kentaro Ito, Mariya Kazachkova, William N. Colgan, Allison Warren, Joshua M. Dempster, John M. Krill-Burger, Maria Ericsson, Andrew A. Tang, Iris Fung, Emily S. Chambers, Mai Abdusamad, Nancy Dumont, John G. Doench, Federica Piccioni, David E. Root, Jesse Boehm, William C. Hahn, Michael Mannstadt, James M. McFarland, Francisca Vazquez, Todd R. Golub
2020
Scaffold hopping enables direct access to more potent PROTACs with in vivo activity
George M. Burslem, Daniel P. Bondeson, Craig M. Crews
2019
Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation
George M. Burslem, Anna Reister Schultz, Daniel P. Bondeson, Christopher A. Eide, Samantha L. Savage Stevens, Brian J. Druker, and Craig M. Crews
2018
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
Daniel P. Bondeson, Blake E. Smith, George M. Burslem, Alexandru D. Buhimschi, John Hines, Saul Jaime-Figueroa, Jing Waang, Brian D. Hamman, Alexey Ishchenko, Craig M. Crews
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study
George M. Burslem, Blake E. Smith, Ashton C. Lai, Saul Jaime-Figueroa, Daniel C. McQuaid, Daniel P. Bondeson, Momar Toure, Hanqing Dong, Yimin Qian, Jing Wang, Andrew P. Crew, John Hines, Craig M. Crews
2016
Targeted Protein Degradation by Small Molecules
Daniel P. Bondeson and Craig M. Crews
2015
Catalytic in vivo protein knockdown by small-molecule PROTACs
Daniel P Bondeson, Alina Mares, Ian ED Smith, Eunhwa Ko, Sebastien Campos, Afjal H Miah, Katie E Mulholland, Natasha Routly, Dennis L buckley, Jeffrey L gustafson, Nico Zinn, Paola Grandi, Satoko Shimamura, Giovanna Bergamini, Maria Faelth-Savitski, Marcus Bantscheff, Carly Cox, Deborah A Gordon, Ryan R Willard, John J Flanagan, Linda N Casillas, Bartholomew J Votta, Willem den Besten, Kristoffer Famm, Laurens Kruidenier, Paul S Carter, John D Harling, Ian churcher, and Craig M Crews
2012
In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis
Taku Hirata, Pablo Cabrero, Donald S. Berkholz, Daniel P. Bondeson, Erik L. Ritman, James R. Thompson, Julian A. T. Dow, and Michael F. Romero
Ion and solute transport by prestin in Drosophila and Anopheles
Taku Hirata, Anna Czapar, Lauren R Brin Alyona Haritonova, Daniel P Bondeson, Paul J Linser, Pablo Cabrero, Julian A T Dow, Michael F Romero
Daniel Bondeson
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368 Plantation Street
Office AS6.2055
Worcester MA, 01605
Bondeson Lab
368 Plantation Street
Lab AS6.2013
Worcester MA 01605