We are excited to welcome Amirshayan (Shaun) Chadeganipour as the inaugural Research Associate for the...
The lab is open and very empty on the 7th floor of the Albert Sherman Center of UMass Chan
This summer has been bittersweet to say goodbye to the Golub lab and to my time at the Broad Institute. It was good to celebrate with kayaking and dinner! There’s nothing like being a quick walk away from a Kayak launch on the Charles River Thank you Saoirse for...
Abstract: Conditional degron tags (CDTs) are a powerful tool for target validation that combines the kinetics and reversible action of pharmacological agents with the generalizability of genetic manipulation. However, successful design of a CDT fusion protein often...
Abstract: Despite advances in precision medicine, the clinical prospects for patients with ovarian and uterine cancers have not substantially improved. Here, we analyzed genome-scale CRISPR–Cas9 loss-of-function screens across 851 human cancer cell lines and found...